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Published on: March 21, 2018

PIK3CA cancer mutations display gender and tissue specificity patterns

Silvia Benvenuti1, Milo Frattini, Sabrina Arena

  • 1Laboratory of Molecular Genetics, The Oncogenomics Center, Institute for Cancer Research and Treatment (IRCC), University of Torino Medical School, Candiolo, Italy.

Human Mutation
|November 21, 2007
PubMed
Summary

Phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) mutations show gender and tissue specificity in cancer. PIK3CA mutations are more common in women with colorectal cancer and predominantly occur in exon 20 in male breast cancer.

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