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Updated: Jul 10, 2026

Retroductal Submandibular Gland Instillation and Localized Fractionated Irradiation in a Rat Model of Salivary Hypofunction
Published on: April 24, 2016
Radiation-induced mandibular adult spindle cell rhabdomyosarcoma
V Goosens1, I Van den Berghe, C De Clercq
1AZ Sint-Jan AV Brugge, Ruddershove 10, 8000 Brugge, Belgium.
Abstract:
Spindle cell rhabdomyosarcoma (RMS), a variant of embryonal RMS, is a rare tumour, especially in adults. Imaging techniques are used to evaluate the extent of the tumour whereas a biopsy is required to make the final diagnosis. In this article we describe a case of mandibular Spindle cell RMS in a previously irradiated field in a 56-year-old male, and discuss the clinicopathologic and imaging findings. Although the aetiology is still unclear, this case suggests that previous radiation therapy can be a causal factor.
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