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Immunotherapies for Hodgkin's lymphoma

Yvette L Kasamon1, Richard F Ambinder

  • 1Division of Hematologic Malignancies, Johns Hopkins Medical Institutions, Baltimore, MD, USA. ykasamo1@jhmi.edu

Critical Reviews in Oncology/Hematology
|November 21, 2007
PubMed

Multiple immune evasion strategies characterize the pathobiology of Hodgkin's lymphoma. These must be considered when developing and testing immunotherapeutic approaches for this disease. The clinical experience with adoptive immunotherapy of Epstein-Barr virus positive tumors, and with monoclonal antibodies directed against CD30, CD20, and other antigens, is herein reviewed.

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