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Updated: Jul 10, 2026

A Macrophage Reporter Cell Assay to Examine Toll-Like Receptor-Mediated NF-kB/AP-1 Signaling on Adsorbed Protein Layers on Polymeric Surfaces
Published on: January 7, 2020
Macrophage receptors implicated in the "adaptive" form of innate immunity
D M E Bowdish1, M S Loffredo, S Mukhopadhyay
1Sir William Dunn School of Pathology, University of Oxford, 10 South Parks Road, Oxford OX1 3RE, UK.
Abstract:
The adaptive component of innate immunity occurs during the course of infection when antigen presenting cells alter expression of soluble or surface associated pattern recognition receptors. This results in increased recognition of a broad spectrum of pathogens, enhancement of effector functions and altered regulation of the inflammatory response.
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