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Cortical Bone Assessment Using Ultrasonic Guided Waves: A Reproducibility Study in a Healthy Population
Published on: January 31, 2025
Experimental and numerical identification of cortical bone permeability
Etienne Malachanne1, David Dureisseix, Patrick Cañadas
1Laboratoire de Mécanique et Génie Civil, Université Montpellier 2/CNRS UMR 5508, Place Eugène Bataillon, CC 048, F-34095 Montpellier Cedex 5, France. malachanne@lmgc.univ-montp2.fr
Journal of Biomechanics
|November 21, 2007
Summary
This study determined the macroscopic permeability coefficient of cortical bone, a key factor in its poroelastic behavior. The findings confirm existing literature values and highlight the significant role of vascular structures in bone
Area of Science:
- Biomechanics
- Materials Science
- Fluid Dynamics
Background:
- Cortical bone exhibits complex poroelastic properties.
- Understanding bone permeability is crucial for modeling its mechanical behavior.
Purpose of the Study:
- To identify the macroscopic permeability coefficient of cortical bone.
- To validate experimental findings with computational analysis.
Main Methods:
- Developed a simple experimental setup to measure fluid flow and pressure in bone samples.
- Utilized finite element method (FEM) for structural computation.
- Coupled experimental data with computational modeling.
Main Results:
- Identified a mean cortical bone permeability coefficient of approximately k=1.1x10(-13)m(2).
- Experimental results were consistent with values reported in existing literature.
- Confirmed the dominant contribution of vascular permeability (Haversian and Volkmann's canals).
Conclusions:
- The determined permeability coefficient aligns with macroscopic values from other studies.
- Vascular networks significantly influence the overall permeability of cortical bone.
- The coupled experimental and computational approach provides a reliable method for assessing bone permeability.
