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Systemic diseases in non-inflammatory branch and central retinal artery occlusion--an overview of 416 patients
Dieter Schmidt1, A Hetzel, A Geibel-Zehender
1University Eye Hospital, Killianstr. 5, 79106 Freiburg, Germany. Dieter.Schmidt@uniklinik-freiburg.de
Insights
Cardiovascular risk factors are common in patients with retinal arterial occlusions like BRAO and CRAO. No significant differences were found in risk factors among these conditions, suggesting comprehensive screening for all patients.
Area of Science:
- Ophthalmology
- Cardiology
- Vascular Medicine
Background:
- Cardiovascular risk factors are frequently observed in patients with vascular ocular diseases.
- Understanding the prevalence of these factors is crucial for managing conditions such as Branch Retinal Artery Occlusion (BRAO) and Central Retinal Artery Occlusion (CRAO).
Purpose of the Study:
- To determine the frequency of essential cardiovascular risk factors in patients diagnosed with different types of vascular ocular diseases.
- To compare the prevalence of these risk factors across specific conditions including BRAO, CRAO, and hemi-CRAO.
Main Methods:
- A retrospective study analyzed cardiovascular risk factor findings in 416 patients with non-inflammatory ocular vascular occlusions.
- Patient data included diagnoses of BRAO (134), CRAO (253), and hemi-CRAO (29).
- Demographic information and the presence of risk factors like hypertension, diabetes, and smoking were compiled.
Main Results:
- Cardiovascular risk factors were identified in 243 out of 416 patients (58.4%).
- Arterial hypertension was the most prevalent risk factor, present in 75.9% of patients.
- No statistically significant differences in major cardiovascular risk factors (hypertension, carotid artery disease, diabetes, hyperlipidemia, hyperuricemia, smoking) were observed between patients with BRAO, CRAO, or hemi-CRAO.
Conclusions:
- There are no significant statistical differences in cardiovascular risk factors among patients with BRAO, CRAO, or hemi-CRAO.
- The study emphasizes the necessity of a comprehensive cardiovascular risk factor examination for all patients presenting with retinal arterial obstruction.
Background:
To determine the frequency of essential cardiovascular risk factors in different vascular ocular diseases. -
Methods:
We compiled cardiovascular risk factor findings (RFs) from 416 patients with non-inflammatory ocular vascular occlusions in a retrospective study: 134 patients with BRAO, 253 patients with CRAO, and 29 patients with hemi-CRAO. 274 (65.9 %) male and 142 (34.1 %) female patients were examined. Mean age of all patients was 66 years (range: 18-90). The right eye was involved in 221 (53.1 %), left eye in 193 (46.4 %), and both eyes in 2 patients (0.5 %). -
Results:
Cardiovascular risk factors (RFs) were found in 243 patients. Three hundred and eight (308) out of 406 patients (75.9 %) presented with arterial hypertension. Hypertension was present in 96 patients with BRAO (73.8 %), in 197 patients with CRAO (79.8 %), and in 15 patients with hemi-CRAO (78.9 %). - RFs such as arterial hypertension, carotid artery diseases, diabetes mellitus, hyperlipidemia, hyperuricemia, and chronic smoking did not differ statistically between patients with BRAO, CRAO or hemi--CRAO. But visible emboli in retinal arteries were observed in patients with BRAO (47 %,), or hemi-CRAO (41.4 %), much more often than in patients with CRAO (11.1 %). -
Conclusions:
No statistical differences between the RFs of patients with BRAO, CRAO, or hemi-CRAO were noted. We maintain that every patient with retinal arterial obstruction should undergo extensive examination of essential RFs.
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