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Updated: Jul 10, 2026
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
Published on: November 7, 2025
Prostate cancer: MR imaging-guided galvanotherapy--technical development and first clinical results
Thomas J Vogl1, Heinz P Mayer, Stefan Zangos
1Department of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Johann Wolfgang Goethe-University, Theodor-Stern Kai 7, D-60590 Frankfurt am Main, Germany. t.vogl@em.uni-frankfurt.de
Radiology
|November 21, 2007
Summary
Magnetic resonance imaging-guided galvanotherapy safely treats prostate cancer, significantly reducing tumor volume and prostate-specific antigen (PSA) levels. This innovative treatment offers local control for prostatic carcinoma.
Area of Science:
- Oncology
- Medical Imaging
- Urology
Background:
- Prostate cancer requires effective and safe treatment options.
- Minimally invasive therapies are increasingly important in oncology.
Purpose of the Study:
- To prospectively evaluate the safety and effectiveness of magnetic resonance (MR) imaging-guided galvanotherapy for prostate cancer treatment.
Main Methods:
- Forty-four men with prostate cancer underwent MR imaging-guided galvanotherapy with transgluteal electrode placement.
- Direct current was applied three times at 1-week intervals.
- Tumor volume and prostate-specific antigen (PSA) levels were monitored for 12 months post-procedure.
Main Results:
- The procedure was well-tolerated with minimal side effects.
- Tumor volume decreased by 41% (median 1.90 to 1.12 cm³).
- Median PSA levels decreased by 66% (7.05 to 2.4 ng/mL) over 12 months.
Conclusions:
- MR imaging-guided galvanotherapy is a safe and effective treatment for prostate cancer.
- The procedure achieves local control of prostatic carcinoma.
- A significant reduction in PSA levels was observed post-treatment.
