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Related Experiment Video

Updated: Jul 10, 2026

Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
05:49

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The antiphospholipid syndrome.

Jacob H Rand1

  • 1Department of Pathology, Montefiore Medical Center, 111 East 210th St, Bronx, NY 10467, USA. jrand@montefiore.org

Hematology. American Society of Hematology. Education Program
|November 21, 2007
PubMed
Summary

Antiphospholipid syndrome (APS) is an autoimmune disorder causing blood clots and pregnancy issues. This update reviews current diagnostic and treatment strategies for APS management.

Area of Science:

  • Immunology
  • Hematology
  • Obstetrics & Gynecology

Background:

  • Antiphospholipid syndrome (APS) is an autoimmune thrombophilic condition.
  • It is characterized by antibodies targeting phospholipid-binding proteins.
  • Clinical features include vascular thrombosis and pregnancy complications like recurrent miscarriages.

Purpose of the Study:

  • To provide an update on the diagnostic approaches for APS.
  • To review the current therapeutic strategies for managing APS.

Main Methods:

  • Literature review of recent advancements in APS diagnosis.
  • Synthesis of current evidence on APS treatment options.

Main Results:

  • Diagnostic criteria for APS have been refined.

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  • Therapeutic options include anticoagulation and antiplatelet agents.
  • Emerging treatments are being investigated for refractory cases.

    • Conclusions:

    • Accurate diagnosis of APS is crucial for timely intervention.
    • Management of APS requires a multidisciplinary approach.
    • Ongoing research aims to improve outcomes for APS patients.