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Published on: December 15, 2011
HLA antigens in Burger's disease
J Zervas1, G Vayopoulos, K Konstantopoulos
1Department of Internal Medicine, Athens University Medical School, Laikon General Hospital, Greece.
Abstract:
The HLA A and B types of 20 Greek patients with thromboangiitis obliterans (TAO) were studied and compared with a panel of 400 controls. A nonstatistically significant increase in the frequencies of HLA B5, B7 and A9 antigens was found. These antigens were found to be associated with a relative risk of 3.47, 3.24 and 2.07 respectively. These findings are partially in agreement with those of a joint English-Swiss study which also found a negative association with B12 antigens; in the Greek population, also of European origin, a negative association was observed with the B8 antigen.
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