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Antibody-Free Assay for RNA Methyltransferase Activity Analysis
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Antibody-Free Assay for RNA Methyltransferase Activity Analysis

Published on: July 9, 2019

RmtC 16S rRNA methyltransferase in Australia

Zhiyong Zong, Sally R Partridge, Jonathan R Iredell

    Antimicrobial Agents and Chemotherapy
    |November 21, 2007
    PubMed
    Abstract

    No abstract available in PubMed .

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    Transfer RNA Synthesis02:36

    Transfer RNA Synthesis

    One of the unique features of tRNA is the presence of modified bases. In some tRNAs, modified bases account for nearly 20% of the total bases in the molecule. Altogether, these unusual bases protect the tRNA from enzymatic degradation by RNases.
    Each of these chemical modifications is carried by a specific enzyme, post-transcription. All of these enzymes have unique base and site-specificity. Methylation, the most common chemical modification, is carried by at least nine different enzymes, with...

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