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Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials

Published on: August 13, 2019

Injectable calcium hydroxylapatite for orbital volume augmentation.

M Reza Vagefi¹, Tristan F W McMullan, John R Burroughs

¹Center for Facial Appearances, 1002 E South Temple, Salt Lake City, UT 84102, USA. info@centerforfacialappearances.com

Archives of Facial Plastic Surgery

|November 21, 2007

Summary

Injectable calcium hydroxylapatite offers a safe and effective method for correcting anophthalmic enophthalmos by augmenting orbital volume. This semipermanent filler provides lasting aesthetic improvement for over a year with minimal loss.

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Three-Dimensional Reconstruction of Orbital Fractures

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Published on: May 16, 2025

Area of Science:

Ophthalmology
Plastic Surgery
Biomaterials

Background:

Anophthalmic enophthalmos presents aesthetic and functional challenges.
Existing orbital volume augmentation methods may be invasive or costly.

Purpose of the Study:

To introduce and evaluate injectable calcium hydroxylapatite for orbital volume augmentation.
To assess the safety, efficacy, and longevity of this new technique for anophthalmic enophthalmos correction.

Main Methods:

Retrospective review of 4 consecutive patients.
Injectable calcium hydroxylapatite (Radiesse) was placed in the extraconal space.
Measurements of enophthalmos using Hertel exophthalmometry were taken pre- and post-procedure.

Main Results:

A mean reduction of 2.75 mm in enophthalmos was observed.
All patients showed clinical and aesthetic improvement lasting over one year.
One case of peribulbar hemorrhage occurred, resolving without sequelae.

Conclusions:

Injectable calcium hydroxylapatite is a safe, simple, and cost-effective option for orbital volume deficiency.
The semipermanent filler provides lasting augmentation (1+ year) with minimal volume loss.
The procedure is repeatable, titratable, and can be performed under local anesthesia in an office setting.