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Published on: January 9, 2015
Wilson's disease presenting as isolated obsessive-compulsive disorder
B L Kumawat1, C M Sharma, Gautam Tripathi
1Department of Neurology, SMS Medical College, Jaipur, Rajasthan, India. kumawatbl@indiatimes.com
Wilson's disease (WD), a genetic disorder, can rarely present as isolated obsessive-compulsive disorder (OCD). Early diagnosis and treatment with chelating agents and behavioral therapy are crucial for managing this rare neurological manifestation.
Area of Science:
- Neurogenetics
- Neuropsychiatry
Background:
- Wilson's disease (WD) is a rare genetic neurodegenerative disorder.
- It presents with diverse symptoms, often involving liver and neuropsychiatric issues.
Observation:
- A 17-year-old male presented with isolated obsessive-compulsive disorder (OCD) symptoms.
- He showed no improvement with standard fluoxetine treatment for OCD.
- Subsequent diagnosis revealed Wilson's disease as the underlying cause.
Findings:
- Wilson's disease can manifest with isolated psychological symptoms, such as OCD.
- Chelating agents and behavioral therapy proved effective in treating the patient's WD-related OCD.
Implications:
- This case highlights the importance of considering Wilson's disease in patients with unexplained OCD.
- It underscores the need for comprehensive diagnostic evaluation for rare neurological disorders presenting with psychiatric symptoms.
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