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Updated: Jul 10, 2026

A Method to Study the C924T Polymorphism of the Thromboxane A2 Receptor Gene
Published on: April 1, 2019
No relation between angiotensin-converting enzyme gene polymorphism and pseudoexfoliation
Oya Tekeli1, M Erol Turaçli, Buket Altinok
1Department of Ophthalmology, Faculty of Medicine, Ankara University, Ankara, Turkey. oyatekeli@tr.net
Aims:
To determine the association between the angiotensin-converting enzyme insertion/deletion (I/D) polymorphism and pseudoexfoliation (PEX) in Turkish patients.
Methods:
This prospective study consisted of 89 patients with PEX, and 120 controls. The I/D polymorphism of the angiotensin-converting enzyme gene was measured with the use of the polymerase chain reaction method.
Results:
The distribution of the polymorphism was not significantly different in cases with PEX and controls. The frequencies of the I and D alleles were not significantly different between the groups.
Conclusion:
According to our findings, I/D polymorphism in the angiotensin-converting enzyme gene does not play any role in the pathogenesis of PEX.
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