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Cystatin C modulates cerebral beta-amyloidosis

Stephan A Kaeser1, Martin C Herzig, Janaky Coomaraswamy

  • 1Department of Cellular Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Otfried-Müller Strasse 27, D-72076 Tübingen, Germany.

Nature Genetics
|November 21, 2007
PubMed
Summary

Genetic variations in the CST3 gene impact cystatin C levels, influencing Alzheimer's disease risk. Lower cystatin C is linked to increased susceptibility, while higher levels may reduce amyloid-beta deposition.

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