Related Experiment Video

Updated: Jul 10, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
11:17

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

[Changes in antibiotic consumption among day-care children in Oslo]

Anne-Lise Nordlie1, Bjørg Marit Andersen

  • 1Avdeling for helsefag Høgskolen i Oslo Postboks 4 St. Olavs plass 0130 Oslo. anne-lise.nordlie@hf.hio.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|November 21, 2007
PubMed

Insights

Antibiotic use and doctor visits decreased significantly in Oslo day-care children between 2000 and 2006. This study tracked infections and antibiotic prescriptions in young children attending daycare facilities.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Context:

  • Day-care children in Oslo exhibited high rates of infection (97%) and antibiotic consumption (65%) in 2000.
  • A previous study in 2000 established a baseline for antibiotic use and infection rates in this population.
  • Concerns regarding antibiotic overuse prompted a follow-up investigation.

Purpose:

  • To assess changes in antibiotic prescriptions and infection treatment among day-care children in Oslo.
  • To compare antibiotic consumption and infection rates between 2000 and 2006.
  • To evaluate the impact of potential interventions or shifts in medical practice on antibiotic prescribing habits.

Summary:

  • A 2006 questionnaire study involving 605 parents (53% participation) from 22 Oslo day-care centers revealed a decrease in treated infections from 65% in 2000 to 50% in 2006.
  • Antibiotic treatment rates for infections dropped from 29% to 20%.
  • Specific reductions were noted in ear infections (75% to 62%) and throat infections (85% to 53%), with medical consultations leading to prescriptions decreasing from 80% to 50%.

Impact:

  • Demonstrates a significant reduction in antibiotic use and medical consultations for infections in Oslo's day-care population.
  • Highlights a potential positive trend in antimicrobial stewardship among young children.
  • Provides valuable data for public health initiatives aimed at optimizing antibiotic prescribing practices in pediatric populations.
Abstract

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