Development of visual evoked potentials following intrauterine growth retardation

Visual evoked potentials to flash (FVEP) were recorded in 23 symmetrically growth retarded newborns of between 32 and 39 weeks gestational age and 41 normally grown controls. At 9 months post term FVEP recordings were repeated in 14 of the growth retarded and 26 of the control infants. The development of two long latency negative components of the wave form of the neonatal FVEP was delayed in the growth retarded infants. The amplitude of a long latency negative peak in the 9 month post term FVEP was reduced in the growth retarded infants. We suggest that intrauterine growth retardation may affect the development of secondary activity in the visual cortex.