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Combinations of ancestral modules in proteins

Yehoshua Sobolevsky1, Zakharia M Frenkel, Edward N Trifonov

  • 1Genome Diversity Center, Institute of Evolution, University of Haifa, Haifa 31905, Israel.

Journal of Molecular Evolution
|November 21, 2007
PubMed
Summary

Twenty-seven omnipresent protein sequence elements, conserved since the last universal common ancestor (LUCA), were identified in prokaryotic proteomes. These elements, forming closed-loop modules, suggest a common evolutionary origin and may illuminate early protein evolution.

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