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Fanconi's anemia: a clinico-hematological and cytogenetic study
U H Athale1, S R Rao, P R Kadam
1Department of Medical Oncology, Tata Memorial Hospital, Parel, Bombay.
Indian Pediatrics
|September 1, 1991
Abstract:
Eleven patients with typical features of Fanconi's anemia with cytogenetic studies were evaluated. Cytogenetic abnormalities was seen in all but one patient. Two patients had acute non-lymphoblastic leukemia (ANLL) and nine had Fanconi's anemia (FA). All patients with FA responded to oxymetholone and are well with a median follow up of 38.6 months. Both patients with ANLL died. This study stresses the need of an accurate cytogenetic analysis in FA patients along with a clinicohematological correlation.