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Updated: Jul 10, 2026

Development of Combinatorial Therapeutics for Spinal Cord Injury using Stem Cell Delivery
Published on: June 7, 2024
Cell therapy for spinal cord regeneration
Stephanie M Willerth1, Shelly E Sakiyama-Elbert
1Department of Biomedical Engineering, Washington University in St. Louis, MO 63130, USA.
Abstract:
This review presents a summary of the various types of cellular therapy used to treat spinal cord injury. The inhibitory environment and loss of axonal connections after spinal cord injury pose many obstacles to regenerating the lost tissue. Cellular therapy provides a means of restoring the cells lost to the injury and could potentially promote functional recovery after such injuries. A wide range of cell types have been investigated for such uses and the advantages and disadvantages of each cell type are discussed along with the research studying each cell type. Additionally, methods of delivering cells to the injury site are evaluated. Based on the current research, suggestions are given for future investigation of cellular therapies for spinal cord regeneration.
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