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Cervical screening in under 25s: a high-risk young population
1Department of Obstetrics and Gynaecology, University Hospital Lewisham, London SE 13 6LH, United Kingdom.
European Journal of Obstetrics, Gynecology, and Reproductive Biology
|November 22, 2007
Summary
Young women under 25 are vulnerable to precancerous cervical lesions. Delaying cervical screening may miss high-grade lesions, increasing cervical cancer risk in this sexually active population.
Area of Science:
- Gynecology
- Oncology
- Public Health
Background:
- UK NHS cervical screening program changes in April 2004 recommended initiating screening at 25 years, shifting from 20 years.
- Concerns exist that this delay may increase cervical cancer risk in younger women.
Purpose of the Study:
- To analyze Papanicolaou smear diagnoses in women under 25 in Lewisham, London.
- To determine the incidence of cervical intraepithelial neoplasia (CIN) in this age group.
Main Methods:
- Analysis of 2793 Pap smear results from women aged under 25 (2617 aged 20-24, 176 under 20) from April 2003 to March 2004.
- Follow-up of colposcopy referrals and cervical biopsy results.
Main Results:
- 7.4% of smears showed mild dyskaryosis and 2.5% showed high-grade lesions.
- Of 182 women referred to colposcopy, 34% had high-grade precancerous lesions (CIN 2 or 3).
- 13% had normal colposcopy results, and 22% did not attend.
Conclusions:
- Young women under 25 in Lewisham are susceptible to precancerous cervical lesions, potentially linked to high sexual activity.
- Absence of screening in this demographic may lead to missed high-grade lesions that could progress to cervical cancer.
- Cervical screening is crucial for the vulnerable, sexually active population under 25.
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