Assessment of low signal adjacent to the falciform ligament on contrast-enhanced MRI
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Published on: September 22, 2023
Michael Macari1, Rita Yeretsian, James Babb
1Department of Radiology, Abdominal Imaging, New York University School of Medicine, Tisch Hospital, 560 First Ave., Ste. HW 202, New York, NY 10016, USA. michael.macari@nyumc.org
Objective:
Geographic low signal in the medial segment of the liver seen on contrast-enhanced MRI has been attributed to focal fatty infiltration. Using in- and opposed-phase gradient-recalled echo (GRE) T1-weighted MRI, we attempted to determine if this finding represents focal fatty infiltration.
Materials And Methods:
From a radiology information system, we identified 174 consecutive patients who underwent contrast-enhanced abdominal MRI. Subjects with diffuse liver disease were excluded. The presence of geographic low signal adjacent to the falciform ligament in the anterior medial aspect of the medial segment of the liver during dynamic gadolinium-enhanced imaging was assessed during the arterial, portal venous, and equilibrium phases of enhancement. If this finding was present on any contrast-enhanced sequence, in- and opposed-phase images were qualitatively evaluated to determine if signal loss occurred on opposed-phase imaging.
Results:
Fifty-three patients were excluded because of diffuse liver disease. Twenty-one (17.4%) of the remaining 121 patients showed focal low signal during gadolinium-enhanced MRI. This finding was present in all 21 patients during the portal venous phase and in seven and five during the arterial and equilibrium phases of enhancement, respectively. Of the 21 patients, three showed signal loss on opposed-phase imaging and 18 (85.7%) did not.
Conclusion:
Although low attenuation or signal adjacent to the falciform ligament may represent focal fat, it usually does not and is likely related to anomalous venous drainage into the liver.
Insights
Geographic low signal near the falciform ligament on MRI is often mistaken for fatty infiltration. This study found it typically represents anomalous venous drainage, not focal fat.
Area of Science:
- Radiology
- Medical Imaging
- Hepatology
Background:
- Geographic low signal in the medial liver segment on contrast-enhanced MRI is commonly attributed to focal fatty infiltration.
- This finding is often observed adjacent to the falciform ligament.
Purpose of the Study:
- To investigate whether geographic low signal in the medial liver segment on contrast-enhanced MRI represents focal fatty infiltration.
- To differentiate focal fatty infiltration from other causes using in- and opposed-phase gradient-recalled echo (GRE) T1-weighted MRI.
Main Methods:
- Reviewed contrast-enhanced abdominal MRI scans of 121 patients without diffuse liver disease.
- Assessed for geographic low signal adjacent to the falciform ligament during dynamic gadolinium-enhanced imaging.
- Evaluated in- and opposed-phase GRE T1-weighted images for signal loss to determine the presence of focal fat.
Main Results:
- Twenty-one patients (17.4%) exhibited focal low signal adjacent to the falciform ligament.
- This finding was consistently present during the portal venous phase.
- Only three patients showed signal loss on opposed-phase imaging, suggesting it is not typically focal fat.
Conclusions:
- Geographic low signal adjacent to the falciform ligament on contrast-enhanced MRI is usually not focal fatty infiltration.
- Anomalous venous drainage into the liver is a more likely cause for this imaging finding.
- In- and opposed-phase MRI can help differentiate causes of focal liver signal abnormalities.
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