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Related Concept Videos

Endoscopic Procedures II: Colonoscopy01:25

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Serum Laboratory Studies, Stool Test, Breath Test01:30

Serum Laboratory Studies, Stool Test, Breath Test

Gastrointestinal (GI) diagnostic studies are pivotal in confirming, ruling out, diagnosing, or staging various diseases, including cancers. Following diagnosis, allocating time for discussions with the patient and providing informational resources is crucial. Diagnostic assessments of the GI tract often occur in outpatient settings like endoscopy suites or GI labs. Preparation for these tests may include dietary restrictions, fasting, liquid bowel preparations, laxatives, enemas, and the...

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Updated: Jul 10, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
07:35

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection

Published on: June 8, 2020

[Screening of colorectal neoplasm].

G Layer1, J F Riemann

  • 1Zentralinstitut für Diagnostische und Interventionelle Radiologie, Klinikum der Stadt Ludwigshafen gGmbH, Akademisches Lehrkrankenhaus der Johannes Gutenberg Universität Mainz, Ludwigshafen, Deutschland. layerg@klilu.de

Der Radiologe
|November 22, 2007
PubMed
Summary

Colorectal carcinoma (CRC) screening in Germany is recommended due to high incidence and preventable nature. Early detection and prevention strategies, like fecal occult blood tests and colonoscopies, significantly reduce CRC mortality and incidence.

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Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

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Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
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Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing
15:17

Colorectal Cancer Cell Surface Protein Profiling Using an Antibody Microarray and Fluorescence Multiplexing

Published on: September 25, 2011

Area of Science:

  • Oncology
  • Gastroenterology
  • Preventive Medicine

Context:

  • Colorectal carcinoma (CRC) poses a significant health burden in Germany, with approximately 29,000 deaths in 2002.
  • The risk of CRC increases with age, affecting 4-6% of the population, particularly those over 50.
  • A high prevalence of precancerous polyps (one-third of individuals over 50) underscores the need for screening.

Purpose:

  • To evaluate the efficacy of CRC screening and prevention strategies.
  • To highlight the potential of early detection and intervention in reducing CRC mortality and incidence.
  • To emphasize the economic benefits of preventive measures over treatment.

Summary:

  • Fecal occult blood testing for individuals aged 45-80 can decrease CRC mortality by 14%.
  • Regular sigmoidoscopies with polypectomy could potentially reduce CRC incidence by 50-70%.
  • Colonoscopy is identified as the optimal method for secondary CRC prevention, offering both diagnosis and treatment with minimal risk.

Impact:

  • Preventive strategies for CRC are strongly supported by available data.
  • Implementing widespread screening and preventive measures can lead to substantial reductions in CRC morbidity and mortality.
  • Economic analyses demonstrate the cost-effectiveness of CRC avoidance strategies compared to treatment.