Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gastrointestinal Motility Disorders01:20

Gastrointestinal Motility Disorders

Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
Gastric Motility01:16

Gastric Motility

Gastric motility is the coordinated contraction and relaxation of stomach muscles that convert ingested food into chyme, a semi-liquid substance ready for further digestion in the intestines. The process begins with the vagus nerve inducing the relaxation of the smooth muscles in the fundus and body of the stomach, allowing these regions to expand and accommodate up to approximately 1.5 liters of food and liquid.
Peristaltic Waves and Chyme Formation
Upon food entry, the stomach initiates...
Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists01:23

Drugs Affecting GI Tract Motility: Serotonin Receptor Agonists

Serotonin, a crucial neurotransmitter synthesized by enterochromaffin cells, plays a cardinal role in regulating gastrointestinal (GI) motility. With over 90% of the body's total serotonin in the GI tract, its influence on digestive processes is profound. Serotonin is swiftly released upon various stimuli, such as food boluses or certain drugs, triggering intrinsic sensory neurons in the myenteric plexus and extrinsic vagal and spinal sensory neurons. This leads to the activation of the...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy01:26

Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy

This lesson explores three gastrointestinal imaging techniques: radionuclide testing, colonic transit studies, and virtual colonoscopy.
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy01:26

Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy

Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists01:28

Drugs Affecting GI Tract Motility: Dopamine Receptor Antagonists

Prokinetic agents are specialized medications that stimulate gastrointestinal (GI) motility, promoting food movement through the GI tract. Dopamine, an inhibitory neurotransmitter, plays a significant role in this process, reducing GI motility and indirectly controlling the speed of digestion. Dopamine receptor antagonists, such as metoclopramide and domperidone, offer a unique advantage as prokinetic agents. By blocking the dopamine receptors, these drugs increase GI motility, improving food...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Early Duodenal Cancer Resected by Using Laparoscopic and Endoscopic Assistance Surgery in a Patient with Peutz-Jeghers Syndrome].

Gan to kagaku ryoho. Cancer & chemotherapy·2024
Same author

[A Rare Case of Cronkhite-Canada Syndrome Associated with Gastric Cancer and Gastric Outlet Obstruction].

Gan to kagaku ryoho. Cancer & chemotherapy·2024
Same author

[Report of Multidisciplinary Treatment for Sisters with Li-Fraumeni Syndrome].

Gan to kagaku ryoho. Cancer & chemotherapy·2023
Same author

[A Case of Curative Resection of a Retroperitoneal Liposarcoma].

Gan to kagaku ryoho. Cancer & chemotherapy·2023
Same author

[A Case of Malignant Peripheral Nerve Sheath Tumor of the Anus Resected by Robot Assisted-APR].

Gan to kagaku ryoho. Cancer & chemotherapy·2023
Same author

[A Case Report of Perianal Paget's Disease Treated with Robot-Assisted Surgery for Positive Margins after Local Excision].

Gan to kagaku ryoho. Cancer & chemotherapy·2023

Related Experiment Video

Updated: Jul 10, 2026

Gastrointestinal Motility Monitor (GIMM)
08:15

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Gastrointestinal motility after digestive surgery.

Erito Mochiki1, Takayuki Asao, Hiroyuki Kuwano

  • 1Department of General Surgical Science, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, Japan.

Surgery Today
|November 22, 2007
PubMed
Summary
This summary is machine-generated.

Postoperative gastrointestinal (GI) motility dysfunction, common after abdominal surgery, involves disrupted cyclic motor activity. New treatments show promise for reducing these common gut motility issues.

More Related Videos

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Related Experiment Videos

Last Updated: Jul 10, 2026

Gastrointestinal Motility Monitor (GIMM)
08:15

Gastrointestinal Motility Monitor (GIMM)

Published on: December 1, 2010

Postoperative Ileus Murine Model
04:26

Postoperative Ileus Murine Model

Published on: July 12, 2024

Area of Science:

  • Gastroenterology
  • Surgical Science
  • Physiology

Background:

  • Gastrointestinal (GI) motility dysfunction frequently complicates abdominal surgery.
  • The interdigestive migrating motor contraction (IMC) is a cyclic motor activity in the fasting upper GI tract, crucial for gut function.
  • Postoperative GI motility issues include absent fed responses, altered IMC phases, and retrograde contractions.

Purpose of the Study:

  • To review the pathophysiology of postoperative GI motility dysfunction.
  • To discuss the role of autonomic nervous dysfunction and hormonal disruptions.
  • To highlight emerging therapeutic strategies for managing postoperative gut dysmotility.

Main Methods:

  • Literature review of studies on postoperative GI motility.
  • Analysis of the mechanisms underlying GI dysmotility after surgery.
  • Evaluation of current and novel treatment approaches.

Main Results:

  • Postoperative GI motility dysfunction is characterized by abnormal IMC patterns and impaired fed responses.
  • Autonomic nervous system dysfunction and hormonal imbalances are key contributors.
  • Motilin agonists can advance phase III contractions, and novel treatments offer improved outcomes.

Conclusions:

  • Postoperative GI motility disorders stem from complex neurohormonal and motor disturbances.
  • Emerging treatments hold significant potential to mitigate the impact of gut dysmotility after surgery.
  • Further research into targeted therapies is warranted to improve patient recovery.