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Pulmonary function studies in healthy school boys of West Bengal
1Department of Physiology, Calcutta University, University College of Science and Technology, India.
Insights
This study established prediction equations for dynamic pulmonary function in healthy West Bengal children aged 9-18. These standards aid in diagnosing obstructive lung diseases, particularly in pediatric cases.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- Establishing normative data for pulmonary function is crucial for diagnosing obstructive lung diseases in children.
- Existing prediction equations may not accurately reflect diverse populations.
Purpose of the Study:
- To derive prediction equations for dynamic pulmonary function measurements in healthy school-going children in West Bengal.
- To provide a baseline for assessing pulmonary health and diagnosing lung diseases in this demographic.
Main Methods:
- Spirometric measurements (FVC, FEV1, MVVF, PEFR) were performed on 328 children aged 9-18 years.
- Measurements followed American Thoracic Society guidelines, using an expirograph and Wright Peak Flow Meter.
- Prediction equations were developed based on age and height.
Main Results:
- Reliable prediction equations were established for FVC, FEV1, MVVF, and PEFR.
- FEF25-75% and FEF75-85% showed high relative variability.
- Pulmonary function values were compared with Indian and international populations, showing variations.
Conclusions:
- The derived prediction equations provide valuable reference standards for West Bengal children.
- These standards can assist in the early detection and management of pediatric obstructive pulmonary diseases.
- Further research may refine predictions for specific lung function parameters.
Abstract:
The establishment of normal standards of dynamic pulmonary function measurements in the form of prediction equations will serve as a remedial measure of different aspects of obstructive pulmonary diseases, especially in children. With a view to achieving the target, dynamic pulmonary function measurements were undertaken on 328 healthy school-going children of West Bengal having age ranging between 9 and 18 years. All the spirometric measurements except PEFR were taken with the help of a 9 l closed-circuit type expirograph following the methods and techniques of American Thoracic Society. PEFR was measured by Wright Peak Flow Meter. Prediction equations were derived on the basis of age and height for all the pulmonary function measurements except FEV1% and FET. The prediction equations for FVC, FEV1, MVVF, and PEFR were reliable, but relative variability of predicted FEF25-75% and FEF75-85% was very large. A comparative study of FVC, FEV1, and PEFR values of our subjects, standardized for age and height, was much closer to the boys of Delhi in FVC but higher than South Indian boys in FEV1, North and South Indian boys in PEFR. In an attempt to compare FVC and FEV1 values of our subjects with foreign populations, it is revealed that boys of our study were much lower than American (White), European, and Jordanian boys but comparable with those of Chinese and Libyan boys.
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