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Updated: Jul 9, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Atrial fibrillation and marijuana smoking
P Korantzopoulos1, T Liu, D Papaioannides
1Department of Cardiology, University of Ioannina Medical School, Ioannina, Greece. p.korantzopoulos@yahoo.gr
Marijuana smoking may trigger atrial fibrillation (AF) in susceptible individuals. This review examines case reports and discusses potential mechanisms linking cannabis use to this heart rhythm disorder.
Area of Science:
- Cardiology
- Pharmacology
- Public Health
Background:
- Marijuana is a widely used illicit substance with increasing prevalence of abuse.
- Cannabis use can impact the cardiovascular system, leading to various adverse events.
- Emerging evidence suggests a potential link between marijuana smoking and atrial fibrillation (AF).
Purpose of the Study:
- To systematically review reported cases of atrial fibrillation (AF) associated with marijuana smoking.
- To explore the potential pathophysiological mechanisms underlying this association.
- To discuss the clinical implications of marijuana-induced AF.
Main Methods:
- Systematic literature search for case reports and studies on marijuana use and AF.
- Analysis of reported cases to identify common characteristics and outcomes.
- Review of existing literature on the cardiovascular effects of cannabinoids.
Main Results:
- Compilation of case reports demonstrating a temporal association between marijuana smoking and AF onset.
- Identification of potential mechanisms including direct electrophysiological effects and sympathomimetic actions.
- Discussion of clinical scenarios where marijuana use may precipitate AF.
Conclusions:
- Marijuana smoking is increasingly implicated as a potential trigger for atrial fibrillation (AF).
- Understanding the underlying mechanisms is crucial for managing patients with cannabis use and cardiac arrhythmias.
- Further research is warranted to confirm causality and guide clinical practice regarding marijuana and cardiovascular health.
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