Related Experiment Video
Updated: Jul 9, 2026
09:51
Screening Bioactive Nanoparticles in Phagocytic Immune Cells for Inhibitors of Toll-like Receptor Signaling
Published on: July 26, 2017
The toll of too much TLR7
1Coley Pharmaceutical Group, 93 Worcester Street, Suite 101, Wellesley, MA 02481, USA. akrieg@coleypharma.com
Immunity
|November 23, 2007
Abstract:
Toll-like receptor 7 (TLR7) detects viral RNA, but can be activated inappropriately by self-RNA, leading to autoimmunity. Deane et al. (2007) show that Tlr7 gene dosage is directly related to the risk of lupus in a mouse model.
