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Updated: Jul 9, 2026

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Sampling and Analysis of Animal Scent Signals
Published on: February 13, 2021
Fragrance material review on cis-alpha-damascone
A Lapczynski1, J Lalko, D McGinty
1Research Institute for Fragrance Materials, Inc., 51 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. alapczynski@rifm.org
Summary
This review examines cis-alpha-damascone, a common fragrance ingredient. It assesses its safety for skin contact and overall toxicologic profile.
Area of Science:
- Toxicology
- Dermatology
- Fragrance Chemistry
Background:
- Cis-alpha-damascone is frequently utilized as a fragrance component in consumer products.
- Understanding its safety profile is crucial for regulatory and consumer protection.
Purpose of the Study:
- To conduct a comprehensive toxicologic and dermatologic review of cis-alpha-damascone.
- To evaluate the safety of cis-alpha-damascone as a fragrance ingredient.
Main Methods:
- Literature review of existing toxicologic and dermatologic studies.
- Analysis of safety data related to cis-alpha-damascone exposure.
Main Results:
- The review synthesizes available data on the toxicologic and dermatologic effects of cis-alpha-damascone.
- Findings address potential risks associated with its use in fragrances.
Conclusions:
- The safety of cis-alpha-damascone as a fragrance ingredient is evaluated based on current scientific evidence.
- Further research may be indicated depending on the review's findings.
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