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Published on: November 21, 2013
Parental history of type 2 diabetes in patients with nonaffective psychosis
Emilio Fernandez-Egea1, Brian Miller, Miguel Bernardo
1Programa Esquizofrenia Clinic, Servel de Psiquiatria, Institut de Neurociencies, Hospital Clinic, Department de Psiquiatria, Universitat de Barcelona, Barcelona, Spain.
Introduction:
We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands.
Methods:
N=34 patients with newly-diagnosed nonaffective psychosis and N=52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes.
Results:
In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p<0.04).
Discussion:
We found an increased prevalence of Type 2 diabetes in the parents of nonaffective psychosis subjects. This association may be due to shared environmental or genetic risk factors, or both.
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