[Electroencephalic changes in patients with brain tumors during chemotherapy]

The purpose of the study was monitoring of EEG changes and their dynamics in patients with brain tumours undergoing chemotherapy. The studies group comprised 115 patients with primary or metastatic brain tumours observed during chemotherapy who had serial EEG examinations. At the beginning of the examinations in the first 2 weeks worsening of the EEG records was found, with increased number of tracings with generalized changes. The automatic analysis of EEG tracings demonstrated in these records increased activity index evidencing increased number of slow waves (delta and theta). Worsening of EEG tracings in the initial period of chemotherapy may be connected with appearance or intensification of brain oedema.