Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Cryptic "chromo-fibroma".

Ryan S Jawitz¹, Kenneth B Calder, Leslie M Turner

¹Lake Erie College of Osteopathic Medicine, Bradenton, FL, USA. rjawitz@lecom.edu

The American Journal of Dermatopathology

|November 23, 2007

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Histopathologic and Immunophenotypic Properties of Primary Cutaneous Large Cell Neuroendocrine Carcinomas.

Journal of cutaneous pathology·2025

Same author

Apocrine Breast Cancer With Psammoma Bodies in a Male Patient.

HCA healthcare journal of medicine·2025

Same author

Synergistic and antagonistic interactions of oxybenzone and ocean acidification: new insight into vulnerable cellular processes in non-calcifying anthozoans.

Frontiers in physiology·2024

Same author

Gene regulation and speciation in a migratory divide between songbirds.

Nature communications·2024

Same author

Permanent Makeup Procedure Heralds the Development of Systemic Sarcoidosis.

Cureus·2022

Same author

Key features of the genetic architecture and evolution of host-microbe interactions revealed by high-resolution genetic mapping of the mucosa-associated gut microbiome in hybrid mice.

eLife·2022

Same journal

Herpetic Whitlow in Association With a Cutaneous Infiltrate of Chronic Lymphocytic Leukemia.

The American Journal of dermatopathology·2026

Same journal

Basal Cell Carcinosarcoma with an Osteosarcomatous Component: A Case Report Supporting the Diagnostic Utility of SATB2 and TRAP Immunostaining with a Literature Review of 22 Cases.

The American Journal of dermatopathology·2026

Same journal

Demonstration of 23-Gene Expression Profile Test Utility Within PRAME Immunohistochemistry Results: A Case Series.

The American Journal of dermatopathology·2026

Same journal

On the Progression From Early-to Late-Stage Melanoma: A Potential Sequence of Molecular Events Using Data From Droplet Digital PCR and Array Comparative Genomic Hybridization, A Pilot Study.

The American Journal of dermatopathology·2026

Same journal

Montgomery Tubercles in the Male Areola: Histological Observations and a Brief About Past Investigators.

The American Journal of dermatopathology·2026

Same journal

Metastatic Syringocystadenocarcinoma Papilliferum Mimicking Cutaneous Squamous Cell Carcinoma of Unknown Primary in a Young Patient.

The American Journal of dermatopathology·2026

See all related articles

Chromoblastomycosis, a chronic fungal infection, can manifest unusually. This study details a rare histopathological finding of spindle cell proliferation in the dermis, offering new insights into fungal disease presentation.

Area of Science:

Dermatopathology
Mycology
Infectious Diseases

Background:

Chromoblastomycosis is a rare, chronic fungal infection affecting the skin and subcutaneous tissues.
It typically presents with diverse clinical manifestations, making diagnosis challenging.
Understanding its histopathological variations is crucial for accurate identification.

Observation:

This report describes an uncommon dermal reaction pattern in chromoblastomycosis.
The observed response involved effacement of the dermis by a proliferation of spindle cells.
These spindle cells were arranged in characteristic sweeping fascicles.

Findings:

The histopathological findings reveal a unique spindle cell proliferation as a response to chromoblastomycosis.

Related Experiment Videos

This presentation differs from more typical granulomatous reactions seen in this infection.

The arrangement of spindle cells in fascicles is a key diagnostic feature.

Implications:

This unusual presentation expands the spectrum of histopathological findings in chromoblastomycosis.
Recognizing this spindle cell pattern is vital for pathologists to avoid misdiagnosis.
Further research may elucidate the mechanisms behind this specific dermal response to fungal pathogens.