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Updated: Jul 9, 2026
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Antigen-Capture Enzyme-Linked Immunosorbent Assay for Specific Detection of Mycoplasma pneumoniae
Published on: February 24, 2023
[Optic neuritis attributable to Mycoplasma pneumoniae].
E Sagui1, E Chazalon, M Bregigeon
1Service de Neurologie, Hôpital d'Instruction des Armées Laveran, Marseille. emmanuel.sagui@laposte.net
Revue Neurologique
|November 23, 2007
Summary
Optic neuritis, an inflammatory eye condition, can be caused by Mycoplasma pneumoniae infection. Early detection through antibody testing is recommended for Mycoplasma pneumoniae-related optic neuritis.
Area of Science:
- Neurology
- Ophthalmology
- Infectious Diseases
Background:
- Optic neuritis (ON) is an inflammatory condition of the optic nerve with often unknown causes.
- Extra-pulmonary manifestations of Mycoplasma pneumoniae (MP) infection can include neurological conditions.
Observation:
- A 26-year-old man presented with sudden bilateral vision loss, diagnosed as ON.
- Cervical spinal cord demyelination and lymphocytic meningitis were observed.
- Mycoplasma pneumoniae specific IgM antibodies were detected, confirming MP infection.
Findings:
- The case highlights a rare presentation of ON linked to Mycoplasma pneumoniae infection.
- Cerebrospinal fluid analysis revealed lymphocytic meningitis with oligoclonal bands.
- Magnetic resonance imaging showed a demyelinating lesion in the cervical spinal cord.
Implications:
- Routine screening for anti-Mycoplasma pneumoniae IgM antibodies is suggested for patients diagnosed with ON.
- This finding expands the understanding of Mycoplasma pneumoniae's neurological impact.
- Prompt diagnosis and potential treatment can lead to favorable outcomes in MP-associated neurological conditions.
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