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Implanting Glass Spinal Cord Windows in Adult Mice with Experimental Autoimmune Encephalomyelitis
Published on: December 21, 2013
Immunomodulatory medicine use in the bi-symptomatic neuro-vertebral conflict
Andrzej Dyszkiewicz1, Tadeusz Szymon Gaździk
1Zakład Komputerowych Systemów Biomedycznych, Instytut Informatyki, Wydział Techniki, Uniwersytet Slaski, Sosnowiec; Laboratorium Biotechnologii, Cieszyn; Niepubliczny Zakład Opieki Zdrowotnej "VIS", Cieszyn.
Abstract:
Background. The following study is an attempt to draw the readers' attention to the issue of the multifariousness of the intervertebral discs' destructive processes resulting in the neuro-vertebral syndrome. The professional literature mentioned here gives a prominence to the thread of immunological phenomena accompanying disc diseases and their treatment.
Material and methods. Selected groups of patients with a high probability of the coexistence of immunological processes were analyzed in terms of pain patterns and topographic cross-sections of the intervertebral discs. They were then treated transdermically with butapirazole and levamisole hydrochloride under the control of Lasegu's bioengineer test, electro-sensory tests and CIC level tests.
Results. A Lasegu's test, an electro-sensory (I) test and a survey showed that the groups of patients treated locally 15 times with Butapirazole showed an almost complete recovery of the symmetry with no effect on the CIC level and the localized pain intensity (II). The majority of the patients experienced a regression of ailments within 3 months. As far as the group of patients treated with Levamisole is concerned both root (I) and localized pains (II) subsided rapidly as confirmed by a survey and a Lasegu's test as well as the electro-sensory tests (I), (II). A high decrease of the level of immunological complexes was noticed after only 15 Levamisole infusions. This correct level was maintained 3 months later, which was shown by further tests.
Conclusions. This seems to be the premise confirming the effect of a localized inflammatory point on the level of immunological complexes present in blood (CIC).
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