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Updated: Jul 2, 2026

Expired CO2 Measurement in Intubated or Spontaneously Breathing Patients from the Emergency Department
Published on: January 30, 2011
False-positive results on colorimetric carbon dioxide analysis in neonatal resuscitation: potential for serious
S M Hughes1, B L Blake, S L Woods
1Eudowood Neonatal Pulmonary Division, Department of Pediatrics, The Johns Hopkins University, Baltimore, MD, USA.
Abstract:
A term infant requiring resuscitation was found to have a false-positive color change on a colorimetric carbon dioxide device as a result of administration of epinephrine via an endotracheal tube. Using models of direct application and vapor exposure with a test lung, we discovered that epinephrine, atropine, infasurf and naloxone may result in false-positive color change. This false-positive response may lead to delayed recognition of esophageal intubation.
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