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Treatment and costs associated with anemic chronic kidney disease patients

Rafia S Rasu1, Tonya Crawford, Harold Manley

  • 1School of Pharmacy, University of Missouri Kansas City, Kansas City, MO 64106, USA. rasur@umkc.edu

Current Medical Research and Opinion
|November 24, 2007
PubMed

Insights

Early detection and treatment of anemia in chronic kidney disease (CKD) patients improve health outcomes. Optimizing therapies like iron and erythropoiesis-stimulating agents (ESAs) is key for managing anemia in CKD.

Area of Science:

  • Nephrology
  • Hematology

Background:

  • Anemia is a common complication in chronic kidney disease (CKD).
  • Anemia in CKD negatively impacts cognitive and physical function.
  • Effective management of anemia is crucial for CKD patient well-being.

Purpose of the Study:

  • To review current therapeutic strategies for anemia in CKD patients.
  • To examine the associated costs of these anemia interventions.

Main Methods:

  • A literature search was conducted using Ovid MEDLINE.
  • Articles published between 1996 and 2007 concerning anemia treatment in CKD were reviewed.

Main Results:

  • Early anemia detection and treatment in CKD patients yield positive cognitive and physical benefits.
  • Therapies enhancing iron availability and erythropoietin production aid in achieving target hemoglobin levels.
  • Awareness of potential medication side effects can prevent further patient injury and reduce healthcare costs.

Conclusions:

  • Healthcare providers should proactively detect and manage anemia in CKD.
  • Further research is needed on erythropoiesis-stimulating agents (ESAs) in predialysis CKD patients.
  • Comparative cost analyses of epoetin and darbepoetin alpha are warranted.
Abstract

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