Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Epilepsy and Seizures: Overview

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...

Epilepsy ll: Types

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.

Electroconvulsive Therapy

Electroconvulsive Therapy

Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early years,...

Psychosurgery

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...

Seizures: Classification

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

Seizures ll: Types

Seizures ll: Types

Seizures are sudden bursts of abnormal electrical discharge in the brain that interfere with normal function. They are commonly divided into three groups: focal seizures, generalized seizures, and other types that do not fit neatly into either category.Focal SeizuresFocal seizures begin in a single brain region. When awareness is preserved, they are called focal aware seizures and may cause sensations such as tingling, unusual smells, or flashing lights. When awareness is impaired, they are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Technical Feasibility of the Endoscopic Endonasal Approach for Clipping an Ophthalmic Artery Aneurysm With an Origin Lateral to the Optic Nerve: A Case Report.

Cureus·2026

Same author

Interictal epileptiform discharges in calcified neurocysticercosis-associated epilepsy: An exploratory study.

Epilepsia·2026

Same author

Diagnostic value of stand-alone videos after inconclusive inpatient EEG-video monitoring.

Epilepsia·2026

Same author

Diagnostic accuracy of multimodal large language models in differentiating epileptic from functional seizures in smartphone recorded videos.

Scientific reports·2026

Same author

Occipital lobe epilepsy presenting as content-specific reading-induced seizures.

Epileptic disorders : international epilepsy journal with videotape·2026

Same author

Rapid EEG in Specific Clinical Situations.

Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society·2026

Search research articles

Related Experiment Video

Updated: Jul 9, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Epilepsy surgery after age 60.

Indrani Acosta¹, Fernando Vale, William O Tatum

¹Comprehensive Epilepsy Program, Departments of Neurology and Neurosurgery, University of South Florida/Tampa General Hospital, Tampa, FL, USA.

Epilepsy & Behavior : E&B

|November 24, 2007

Summary

Temporal lobectomy is effective and safe for older adults (60+ years). Outcomes in this age group are comparable to younger patients, supporting its use in elderly individuals.

More Related Videos

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Published on: October 26, 2014

Related Experiment Videos

Last Updated: Jul 9, 2026

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Anteromesial Temporal Lobectomy for Medically Intractable Temporal Lobe Epilepsy: An Operative Study

Published on: August 15, 2025

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Multi-electrode Array Recordings of Human Epileptic Postoperative Cortical Tissue

Published on: October 26, 2014

Area of Science:

Neurosurgery
Geriatric Medicine
Epilepsy Research

Background:

Temporal lobectomy is a common surgical treatment for refractory epilepsy.
Limited data exist on the efficacy and safety of temporal lobectomy in elderly patients (60 years and older).

Purpose of the Study:

To evaluate the outcomes of temporal lobectomy in patients aged 60 years and older.
To compare the efficacy and safety of temporal lobectomy in elderly patients versus younger cohorts.

Main Methods:

Retrospective review of data from seven patients aged 60 years and older who underwent temporal lobectomy.
Analysis of surgical outcomes and complication rates.

Main Results:

Outcomes in the elderly cohort were comparable to those typically observed in younger patients.
The procedure demonstrated acceptable safety and efficacy in this geriatric population.

Conclusions:

Temporal lobectomy is a viable and safe surgical option for epilepsy management in elderly patients.
Further prospective studies are warranted to confirm these findings in larger cohorts.