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Updated: Jul 9, 2026

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Network-centered view of coronary artery disease
Brian J Bennett1, Casey E Romanoski, Aldons J Lusis
1Department of Medicine, University of California, Los Angeles, CA 90095-1679, USA. bbennett@mednet.ucla.edu
Abstract:
Systems biology is an emerging field that attempts to examine multiple elements of a biologic system using techniques such as expression microarrays or proteomics. The goal of systems biology is to detect all the elements of a system and create an interaction network between these so that the system can be explained under specified conditions. In this review we discuss how systems-based approaches are being applied to cardiovascular disease, illustrating concepts, such as the integration of orthogonal datasets, coexpression networks and emergent properties.
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