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The 4-vessel Sampling Approach to Integrative Studies of Human Placental Physiology In Vivo
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Transplacental metabolic alkalosis

Patrik Schimert1, Vera Bernet-Buettiker, Christoph Rutishauser

  • 1Department of Neonatology and Intensive Care, University Children's Hospital, Zurich, Switzerland.

Journal of Paediatrics and Child Health
|November 27, 2007
PubMed

We present a newborn with hypochloraemic metabolic alkalosis due to severe metabolic alkalosis of his mother. Hypoventilation as a leading symptom resolved quickly with treatment but may be life-threatening if not detected. In this case, the mother had a probable eating disorder. Little is known about transplacentally acquired electrolyte disorders in this setting. In the absence of symptoms, most of the cases might be undetected. The usual neonatal outcome of anorexia and/or bulimia nervosa in pregnancy is a lower birthweight and a lower risk for instrumental delivery.

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