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Updated: Jul 9, 2026

Modifications of the Langendorff Method for Simultaneous Isolation of Atrial and Ventricular Myocytes from Adult Mice
Published on: May 13, 2021
Carl L Backer1, Robert D Stewart, Frédérique Bailliard
1Division of Cardiovascular Thoracic Surgery, and Cardiology, Children's Memorial Hospital, Chicago, IL 60614, USA. cbacker@childrensmemorial.org
The modified single-patch technique offers comparable outcomes to the two-patch technique for complete atrioventricular canal (CAVC) defects. This approach also significantly reduces cross-clamp and cardiopulmonary bypass times in infants.
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