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Steroid-responsive nephrotic syndrome in a child with juvenile idiopathic arthritis
Flavio Bandin1, Marion Merhenberger, Anne Modesto
1Department of Paediatric Nephrology, Children's Hospital, Centre de Référence du Sud-Ouest des Maladies Rénales Rares, Toulouse, France. bandin.f@chu-toulouse.fr
Abstract:
Renal disease is rare in children with juvenile idiopathic arthritis, although a number of associated nephropathies have been described, including mesangial glomerulonephritis. We report the presence of mesangial glomerulonephritis, revealed by a nephrotic syndrome, in a paediatric patient with juvenile idiopathic arthritis. Short-term steroid treatment induced a rapid remission of the nephrotic syndrome, but the presence of anti-nuclear antibodies, 1:320 in a homogeneous pattern, irregular deposits of C1q in a renal biopsy, and a mother with episodes of cutaneous lupus suggested an uncertain renal evolution for this infant.
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