Imaging in unilateral Wilms tumour

Hervé J Brisse1, Anne M Smets, Sue C Kaste

  • 1Service de Radiodiagnostic, Institut Curie, 26 Rue d'Ulm, Paris, France. herve.brisse@curie.net

Pediatric Radiology
|November 27, 2007
PubMed

Insights

Wilms tumour treatment varies globally, impacting imaging choices. This review details radiological techniques for diagnosing paediatric Wilms tumour and assessing metastatic disease.

Area of Science:

  • Pediatric Oncology
  • Radiology
  • Medical Imaging

Background:

  • Wilms tumour is a common childhood malignancy with a good prognosis.
  • Treatment protocols for Wilms tumour differ significantly between Europe (chemotherapy then surgery) and the United States (surgery then chemotherapy).
  • These geographical variations in treatment influence the selection and application of diagnostic imaging modalities.

Purpose of the Study:

  • To discuss the role of various imaging modalities in the diagnosis of Wilms tumour.
  • To compare the strengths and weaknesses of ultrasound (US), computed tomography (CT), and magnetic resonance imaging (MRI) in diagnosing Wilms tumour.
  • To highlight the importance of imaging in treatment planning and detecting metastatic disease.

Main Methods:

  • Review of current radiological techniques used for Wilms tumour diagnosis.
  • Discussion of imaging protocols based on European (SIOP) and US (NWTS) treatment guidelines.
  • Focus on imaging for pulmonary metastases and tumour rupture.

Main Results:

  • Imaging, alongside clinical assessment, aids in predicting Wilms tumour.
  • Preoperative image-guided biopsy is crucial in the UK to differentiate Wilms tumour from other neoplasms.
  • Imaging provides essential anatomical detail for surgical planning in the US protocol.
  • CT is used to detect pulmonary nodules, and tumour rupture at diagnosis is assessed radiologically.

Conclusions:

  • The choice of imaging modality for Wilms tumour diagnosis is influenced by geographical treatment protocols.
  • Accurate radiological assessment is vital for appropriate treatment selection, surgical planning, and monitoring metastatic disease.
  • Understanding the nuances of imaging techniques is critical for optimizing patient outcomes in Wilms tumour management.

Related Concept Videos

Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...