[The autonomic nervous system function in benign prostatic hyperplasia]

BPH is responsible for lower urinary tract symptoms (LUTS). Pathogenesis of prostatic overgrowth is multifactorial. It has been suggested that the autonomic nervous system (ANS) may also be involved. The aim of the study was to evaluate the role of the ANS activity in pathogenesis of BPH. The study was done in 13 men with LUTS secondary to BPH. ANS activity was assessed based on heart rate variability (HRV) measurement in resting conditions and after simulation with deep breathing (DB test) and the tilt test. LUTS (with IPSS scale), quality of life, waist-hip ratio and objective measures of benign prostatic hyperplasia (BPH), were evaluated. Correlation for LF/HF ratio vs. BPH variables was calculated. Results of the study showed sympathetic overactivity and impaired parasympathetic response to stimulation in both DB and tilt test.