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Updated: Jul 9, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antimicrobial prevention and therapy for travelers' infection
Francesco Castelli1, Susanna Capone, Barbara Pedruzzi
1University of Brescia, Unit for Tropical and Imported Diseases, Spedali Civili General Hospital, Piazza Spedali Civili, 1 25123 Brescia, Italy. castelli@med.unibs.it
Abstract:
International journeys are increasing and more than 70 million people from industrialized countries cross the borders of tropical countries every year. More than 50% of them will suffer from some form of infectious illness, ranging from mild travelers' diarrhea to severe dengue fever to fatal malaria, with a wide spectrum of microbiological entities. Travel-related respiratory infections, including TB, and sexually transmitted infections are also increasingly reported. Awareness of travel-related risk is not always adequate among international travelers. Specific training on travel medicine-related issues, as well as better diagnostic facilities for imported diseases, is crucial for physicians and nurses in industrialized countries.
Insights
International travel is rising, with over 70 million people visiting tropical countries annually. Over half experience infectious illnesses, highlighting the need for better travel medicine awareness and diagnostics.
Area of Science:
- Global Health
- Infectious Diseases
- Travel Medicine
Background:
- Increasing international travel to tropical regions poses significant health risks.
- Over 50% of international travelers contract infectious diseases, from mild to fatal.
- Emerging travel-related infections include respiratory diseases like tuberculosis (TB) and sexually transmitted infections.
Purpose of the Study:
- To highlight the growing incidence of infectious illnesses among international travelers.
- To emphasize the inadequate awareness of travel-related health risks.
- To advocate for enhanced travel medicine education and diagnostic capabilities.
Main Methods:
- Analysis of international travel statistics and reported infectious disease cases.
- Review of common and emerging travel-related pathogens and illnesses.
- Assessment of current traveler awareness and healthcare provider preparedness.
Main Results:
- Millions of travelers are affected by a wide spectrum of infectious diseases annually.
- Inadequate traveler awareness contributes to preventable illnesses.
- Physicians and nurses require specialized training in travel medicine.
Conclusions:
- Improved traveler education on infectious disease risks is essential.
- Enhanced diagnostic facilities are crucial for managing imported diseases.
- Strengthening travel medicine infrastructure is vital for global public health.
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