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Related Concept Videos

Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
Decreased Body Temperature01:29

Decreased Body Temperature

A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Endotracheal Tube Extubation01:24

Endotracheal Tube Extubation

Endotracheal tube extubation is a critical procedure in weaning patients from mechanical ventilation. It involves physically removing the oral or nasal endotracheal (ET) tube, marking the final step in liberating a patient from ventilatory support.
Procedure
Extubation removes the endotracheal tube (ETT) from the patient on mechanical ventilation. It requires a well-coordinated, multidisciplinary approach involving physicians, nurses, respiratory therapists, and other healthcare professionals.
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...

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A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds
02:49

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Published on: February 23, 2024

Trace element requirements in critically ill burned patients.

Mette M Berger1, Alan Shenkin

  • 1Adult Intensive Care Medicine & Burns Centre, CHUV, BH-08.660, CH-1011 Lausanne, Switzerland. Mette.Berger@chuv.ch

Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)
|December 6, 2007
PubMed
Summary

Critically ill burn patients often have trace element deficiencies, particularly copper. Early intravenous trace element supplementation can improve recovery, reduce infections, and speed wound healing in these patients.

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Area of Science:

  • Biochemistry
  • Critical Care Medicine
  • Nutritional Science

Background:

  • Critically ill burned patients experience severe oxidative stress, inflammation, and hypermetabolism.
  • Trace element (TE) deficiencies are common and worsen outcomes like organ failure and delayed wound healing.
  • Major burns lead to the most severe TE deficiencies, including specific copper deficiency.

Purpose of the Study:

  • To investigate the impact of trace element deficiencies in critically ill burn patients.
  • To evaluate the efficacy and safety of intravenous trace element supplementation.
  • To determine optimal trace element dosages and delivery routes for improved patient recovery.

Main Methods:

  • Analysis of plasma TE concentrations in critically ill patients, especially those with major burns.
  • Review of intravenous supplementation trials assessing TE substitution.
  • Examination of TE losses through biological fluids and exudative losses.

Main Results:

  • Low plasma TE concentrations are linked to fluid resuscitation, inflammation, and exudative losses.
  • Early intravenous TE supplementation improved recovery, reduced infections (e.g., nosocomial pneumonia), normalized thyroid function, and enhanced wound healing.
  • Specific safe and effective dosages for copper, selenium, and zinc were identified for major burns.

Conclusions:

  • Trace element deficiencies significantly complicate critical illness in burn patients.
  • Intravenous trace element supplementation is crucial for improving clinical outcomes.
  • Further research is needed to optimize TE combinations and doses for varying injury severities.