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3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation
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3D Hydrogel Scaffolds for Articular Chondrocyte Culture and Cartilage Generation

Published on: October 7, 2015

The applicability of an amidated polysaccharide hydrogel as a cartilage substitute: structural and rheological

Gemma Leone1, Maurizio Delfini, Maria Enrica Di Cocco

  • 1CRISMA and Department of Chemical and Biosystem Science and Technologies, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.

Carbohydrate Research
|November 28, 2007
PubMed

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Glycosaminoglycans01:23

Glycosaminoglycans

Glycosaminoglycans (GAGs), also known as mucopolysaccharides, are long and linear polymers comprising of specific repeating disaccharides - the amino sugar that can be N-acetylglucosamine or N-acetylgalactosamine, and a uronic acid that is usually glucuronic acid or iduronic acid.
GAGS are found in the extracellular matrix of vertebrates, invertebrates, and bacteria. Due to their polar nature they attract water, and serve as excellent lubricants or shock absorbers in an animal body.
Hyaluronic...