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Sulfated polyanions do not inhibit duck hepatitis B virus infection
W B Offensperger1, S Offensperger, E Walter
1Department of Medicine, University of Freiburg, Germany.
Antimicrobial Agents and Chemotherapy
|November 1, 1991
Abstract:
On the basis of the antiviral action of sulfated polyanions in human immunodeficiency virus and other viral infections, we studied the effect of dextran sulfate and heparin on duck hepatitis B virus infection. These agents do not affect viral uptake and replication in liver cells in vitro or in vivo. Sulfated polyanions, therefore, appear to have no potential for the treatment of hepadnavirus infections.