Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Circulating immune complexes in Waldeyer's ring hypertrophy.

W Prusek1, M K Mohgoub, M Podwysocka

  • 1Department of Pediatrics, Regional Hospital, Wrocław.

Archivum Immunologiae Et Therapiae Experimentalis
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cadmium, arsenic, selenium and iron- Implications for tumor progression in breast cancer.

Environmental toxicology and pharmacology·2017
Same author

DNA damage and oxidative stress response to selenium yeast in the non-smoking individuals: a short-term supplementation trial with respect to GPX1 and SEPP1 polymorphism.

European journal of nutrition·2015
Same author

MMP, VEGF and TIMP as prognostic factors in recurring bladder cancer.

Clinical biochemistry·2015
Same author

Expression of NRF2 and NRF2-modulated genes in peripheral blood leukocytes of bladder cancer males.

Neoplasma·2012
Same author

Genetic polymorphism of matrix metalloproteinases in breast cancer.

Neoplasma·2012
Same author

[Serotonin metabolism in children infected with Giardia intestinalis].

Wiadomosci parazytologiczne·2006

Circulating immune complexes (CIC) were detected in children with chronic tonsillitis, but not in healthy children or those with tonsil hypertrophy. Surgical removal of tonsils led to the disappearance of these immune complexes.

Area of Science:

  • Pediatric immunology
  • Otolaryngology
  • Immunopathology

Background:

  • Chronic tonsillitis and tonsil hypertrophy are common pediatric conditions.
  • The role of immune complexes in these conditions is not fully understood.
  • Circulating immune complexes (CIC) may indicate underlying inflammatory or autoimmune processes.

Purpose of the Study:

  • To investigate the occurrence of CIC in children with chronic tonsillitis and/or tonsil hypertrophy.
  • To determine if CIC levels change after surgical intervention (tonsillectomy or adenotonsillectomy).

Main Methods:

  • Study included children with chronic tonsillitis, tonsil hypertrophy, or both.
  • A control group of healthy children was included.
  • Circulating immune complexes (CIC) were detected using the PEG precipitation method.

Related Experiment Videos

  • CIC levels were assessed before and after tonsillectomy or adenotonsillectomy.

    • Main Results:

    • CIC were detected in 20 children with chronic tonsillitis and 5 with both conditions.
    • CIC were not detected in healthy children or those with only tonsil hypertrophy.
    • CIC disappeared in all patients within 1-3 months after tonsillectomy or adenotonsillectomy.

    Conclusions:

    • Circulating immune complexes (CIC) are associated with chronic tonsillitis in children.
    • Tonsillectomy or adenotonsillectomy effectively resolves CIC in affected children.
    • These findings suggest a link between tonsillar inflammation and systemic immune complex formation.