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Updated: Jul 9, 2026
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An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
[Photodynamic therapy in angioid streaks]
M Elías-de-Tejada1, C Calvo-González, J Reche-Frutos
1Departamento de Retina del Hospital Clínico San Carlos, Madrid, España. macaelias@yahoo.es
Archivos De La Sociedad Espanola De Oftalmologia
|November 28, 2007
Summary
Photodynamic therapy for choroidal neovascularization due to angioid streaks did not change disease course but slowed progression. This treatment offers a potential strategy for managing this rare condition.
Area of Science:
- Ophthalmology
- Medical Retina
- Vascular Biology
Context:
- Angioid streaks are a rare condition affecting Bruch's membrane.
- Choroidal neovascularization (CNV) is a common complication of angioid streaks.
- Photodynamic therapy (PDT) is a treatment option for CNV.
Purpose:
- To evaluate the efficacy and safety of photodynamic therapy (PDT) for choroidal neovascularization (CNV) associated with angioid streaks.
Summary:
- A retrospective study analyzed eleven eyes with angioid streak-related CNV treated with PDT.
- Visual acuity decreased in most patients, and nine eyes developed fibrotic lesions.
- Recurrence of CNV was observed in three eyes, indicating limited long-term efficacy.
Impact:
- Photodynamic therapy (PDT) may slow the progression of choroidal neovascularization (CNV) in angioid streaks.
- While not altering the disease course, PDT offers a potential method to manage this condition.
- Further research is needed to explore alternative or adjunctive therapies for angioid streak-related CNV.
