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Updated: Jul 9, 2026
A Simple Mechanical Procedure to Create Limbal Stem Cell Deficiency in Mouse
Published on: November 17, 2016
[Sectorial conjunctival epitheliectomy and amniotic membrane transplantation for partial limbal stem cells
D Díaz-Valle1, E Santos-Bueso, J M Benítez-Del-Castillo
1Unidad de Superficie e Inflamación Ocular, Hospital Clínico Universitario San Carlos, Madrid, España. daviddiazvalle@yahoo.es
Case Report:
A 74-year-old man developed a partial limbal stem cell deficiency secondary to a chemical injury in the left eye. He was treated with a sectorial conjunctival epitheliectomy and amniotic membrane transplantation. After 3 weeks there was an intact, smooth and stable corneal epithelium.
Discussion:
This case report emphasizes that conjunctival epitheliectomy and amniotic membrane transplantation appears to be a safe and effective method of restoring a stable corneal epithelium for cases of partial limbal stem cell deficiency.
