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Updated: Jul 9, 2026

Prediction of HIV-1 Coreceptor Usage (Tropism) by Sequence Analysis using a Genotypic Approach
Published on: December 1, 2011
Post-exposure prophylaxis with a maraviroc-containing regimen after occupational exposure to a multi-resistant
Frédéric Méchai1, Yann Quertainmont, Sabrinel Sahali
11/AP-HP, Internal Medicine and Infectious Diseases Department, Bicêtre University Hospital, Paris XI University, Le Kremin-Bicêtre, France.
Abstract:
We report the case of a health care worker who received a post-exposure prophylaxis including an investigational drug, maraviroc, after a needle stick percutaneous injury to an HIV-infected patient with late-stage disease and harboring a multi-drug resistant virus. Post-exposure prophylaxis including maraviroc was pursued for a total of 28 days, with a weekly clinical and biological evaluation. Post-exposure prophylaxis was well tolerated, with no increase in liver function tests. The health care worker remained HIV-negative after a 6-month follow-up.
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