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[Multicentric intestinal angiosarcoma. Report on a case].

J P Deléaval1, M Y Peter, F Laurencet

  • 1Département de Pathologie, Hôpital Cantonal Universitaire de Genève, CMU, Suisse.

Annales De Pathologie
|January 1, 1991
PubMed
Summary
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A rare duodenal angiosarcoma led to persistent bleeding and death in a patient. Autopsy revealed multiple tumors and pulmonary metastases, highlighting diagnostic challenges for this rare digestive tract cancer.

Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Angiosarcoma is an exceptionally rare malignancy, particularly within the digestive tract.
  • Early detection of gastrointestinal angiosarcomas is challenging due to their rarity and often asymptomatic presentation.

Observation:

  • A 74-year-old female presented with anemia, leading to the discovery of a duodenal angiosarcoma.
  • Despite surgical resection, persistent hemorrhage occurred, ultimately leading to patient mortality.

Findings:

  • Autopsy revealed disseminated angiosarcomatosis, including colonic tumors and pulmonary micrometastases.
  • Radiological and angiographic studies failed to confirm the diagnosis, which was established through endoscopic, surgical, and histological examination.

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Implications:

  • This case underscores the diagnostic difficulties associated with rare gastrointestinal angiosarcomas.
  • The propensity for multifocal disease and metastasis necessitates a high index of suspicion and thorough histopathological evaluation.